Im still fairly new to substance, and Im having this issue again, but this time the log file doesn't say if it is UV overlapping issue or an issue with a specific mesh....it just says that it failed to load the 3d scene.
The model was made on blender, I triangulated the mesh and manually unwrapped the meshes.
I tried both FBX and OBJ files and the result was the same for both.
(The error log is attached below)