I'm not quite sure if these are accurate - I'll try to run some more tests when I have a minute but
1. I think navigation in the 3d viewport from left to right is backwards... I reinstalled 5.2.5 and it feels more normal now... but it felt like left went right and right went left in 5.2.5. Like I said I'll reinstall 5.3 and try to confirm this.
2. Some of the updating feels a little sluggish in the 3d viewport. Like it doesn't update all the textures right away. Again I'll to get a more detailed report on this.
Thanks! And regardless - awesome release!!